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Why does hydroquinone cause rebound hyperpigmentation when you stop using it? Hydroquinone destroys tyrosinase irreversibly by denaturing the enzymes copper active site, which triggers melanocytes to upregulate MITF (microphthalmia-associated transcription factor) the master regulator of melanocyte activity as a compensatory response

Formulated with a stable form of vitamin C, this lightweight serum works to diminish the look of unwanted pigmentation

People under high stress : High levels of stress can deplete glutathione, making it harder for the body to protect itself from oxidative damage

The combination increases gastrointestinal side effects