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have metabolic disease or obesity, and only two million people are being treated for metabolic disease with GLP-1-based therapies, signaling an ongoing need for more convenient, cost-effective, well-tolerated mono- and combination therapies.

The breadth of DSIPs biological activity spanning sleep regulation, stress modulation, pain processing, antioxidant defence, and neuroprotection has led some researchers to characterise it as an adaptogenic peptide: one that supports homeostatic balance across multiple physiological systems rather than acting on a single discrete target

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Precise modulation and use of reactive oxygen species for immunotherapy