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In an AD mouse model, GLP-1RAs were demonstrated to reduce the levels of AD pathological markers, including oligomeric antibodies and antibody plaque load, reduce the activation of microglia, and improve memory behavior (35, 44, 45)

Maximum synergism was observed when rutin hydrate was paired with resveratrol in 3:1 proportion, whereas maximum antagonism was observed when rutin hydrate was paired with hydroquinone in 1:3 proportion (145, 146)

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The EPR effect on nanoparticles such as Doxil and Caelyx is sanctioned