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Head-to-head data from the SURMOUNT-5 trial showed tirzepatide producing 20.2% weight loss compared to 13.7% for semaglutide at 72 weeks
This can lead to an imbalance in the gut flora, and can cause inflammation and other problems
The most common adverse events (AEs) were gastrointestinal, including nausea, diarrhea, and constipation, affecting up to 75% of patients treated with Zepbound and 20%40% of patients treated with Wegovy
Your body compensates for this problem by keeping insulin levels high all the time
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