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After the February 2025 shortage resolution and April 22, 2025 enforcement deadline, each prescription requires prescriber evaluation and documented clinical rationale not just shortage status reasoning
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Among them, cystathionine -synthase (CBS), cystathionine -lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3MST) have long been studied based on their roles in H 2 S biogenesis ( 2 S is converted to thiosulfate and sulfate ( Despite the growing understanding of the physiological roles of RSS, the precise contribution of each enzyme to specific biological events remains elusive
Inflammopharmacology 21 (3), 201232 (2013)
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