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In patients with T2DM, the incretin effect is diminished
The most commonly reported side effects include: Nausea the most frequently reported side effect, typically mild to moderate and most common in the first few weeks of treatment Vomiting Diarrhea Constipation Decreased appetite Indigestion or stomach discomfort Fatigue The majority of side effects are gastrointestinal in nature and tend to improve significantly as your body adjusts to the medication
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