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mortality-related g ene) was found to be one of these proliferation promoting proteins, and is targeted for degradation by the E3 ubiquitin ligase RFP-1 (ring finger protein) ( glp-1(gf) background, suggesting that there could be multiple targets whose regulated degradation is necessary for the proliferation vs differentiation decision to be properly maintained (Pepper et al., 2003
Othman, A
Nov 5 2014;312(17):1772-1778
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