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The digest was filtered through a 70-m mesh and centrifuged using a 28.7% Nycodenz gradient (Nycomed PharmaAS, Oslo, Norway)

By developing a user-engagement framework6 that can be used to generate ideas for behavioural interventions at all stages of a task, it is possible to ensure that products resonate on a practical, emotional and aspirational level (Figure 2).This approach, grounded in behavioural science, addresses real-world barriers to medication adherence by mapping engagement touchpoints to drivers of motivation, providing a tool for design teams to think through problems and create solutions that not only function well but also encourage user participation

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