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*Correspondence: Huatian Gan, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Table of Contents How GLP1 Therapies Work Oral vs Injectable: Why the Pill Matters Clinical Evidence Behind Oral GLP1 Agents Practical Considerations in Primary Care Challenges, Side Effects, and Cost Future Directions in Incretin Therapy FAQ Conclusion How GLP1 Therapies Work GLP1 receptor agonists are incretin-based therapies that mimic the bodys natural hormones to improve blood sugar regulation

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Yeo and colleagues also reported an increase in the proportion of new users without FDA-approved indications, which rose from 0.21% to 0.37% between 2019 and 2023