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This suggests that GHK-Cu may have systemic tissue regeneration abilities beyond cosmetic skin rejuvenation
Singer et al., 2014
Biometals 2014
The current standard operating procedure by the European Center for the Validation of Alternative Methods (ECVAM) recommends the use of MTT reduction as parameter to make prediction on the skin irritancy of substances using EpiSkin TM test method, while IL-1 endpoint is regarded as a useful adjunct to MTT assay 48
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