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It causes very negligible side effects and has become popular compared to much harsher treatments

Cash-pay members who fill a branded injectable at a retail pharmacy instead pay the $149/mo membership plus $500-$1,100/mo for the medication, the totals shown above

Its not only considered safe for these purposes, but also likely to improve health significantly, says Jessica Cutler, MD, a weight loss surgeon with the Maryland Bariatric Center at Mercy Medical Center in Baltimore

For a full comparison of these two peptides beyond reconstitution, including mechanism, weight loss data, and side effect profiles, see retatrutide vs tirzepatide