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10.1038/onc.2013.369 Oncogene 157 ZhangY

Although probiotic supplementation shows promising potential in improving thyroid function in thyroid diseases, further human studies on the effects of probiotics as adjuvant therapy for thyroid diseases are required ( Table 1 )

In many regions, medicines such as Tri-Luma or certain hydroquinone combinations are not sold over the counter, yet they can be ordered online for personal use through international supply channels, with shipping times often around 13 weeks after dispatch

Category 2 means the FDA has determined that the substance "may present significant safety risks" when used in compounding