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The mammalian GPX7 gene contains 3 exons, encodes 187 amino acids, and has a predicted molecular weight of 22 kDa

Although they are easy to find and use, glutathione in pill form is absorbed poorly and has lower efficacy than when injected

It is vital for protecting mitochondria, the energy centers of the cell

While they found better skin outcomes in participants who used hydroquinone cream (a common melasma intervention), they also concluded that topical silymarin was also effective and produced fewer side effects.28 Wrinkles A lack of skin moisture is one of the factors behind fine lines and wrinkles.29 According to a 2012 study published in the African Journal of Biotechnology , milk thistle extract, emulsified into a topical cream, may help combat wrinkle formation by boosting moisture retention and preventing transepidermal water loss.30 An important caveat to consider is that all of our top recommended milk thistles are oral supplements, and research on oral milk thistle for the above purposes is somewhat lacking