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These are patterns from real-world reports rather than trial incidence rates
Clinical data support their ability to reduce risks of heart failure (30), atherosclerosis (31), and hypertension (32), highlighting their potential as systemic therapeutics
Nevertheless, comprehensive pharmacokinetic studies in rodents are still lacking, making it difficult to draw firm conclusions
Moreover, we did not evaluate the effects of other glycemic indices such as 2-h post-prandial glucose due to the lack of examination of this outcome in clinical trials
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