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10.1111/j.1467-789X.2005.00212.x 133 MahfoudF.SchlaichM.KindermannI.UkenaC.CremersB.BrandtM
Acknowledgements This paper was funded by grants from the National Natural Science Foundation of China (82070588, 82370577), National Key R&D Program of China (2023YFA1800801)
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Safety Profile in Research Contexts Gastrointestinal events (nausea, vomiting, diarrhea, constipation) remain the most common adverse effects, typically mild to moderate, dose-dependent, and often mitigated by gradual dose escalation starting at lower levels (e.g., 2 mg)
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