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It is true that membrane-permeable iron chelators such as ciclopirox (CPX), 2,2-bipyridyl(2,2-BP) and impermeable iron chelators such as deferoxamine (DFO) provide adequate protection against ferroptotic cell death, while supplementation with exogenous iron sources or transferrin in combination with iron without treating with other divalent metals accelerates ferroptosis (Yagoda et al., 2007
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doi: 10.1016/S0021-9258(17)31254-1 155 BremsDBrownPNakagawaSTagerH
Finally, we also suggest that clients concurrently stack N-acetylcysteine (NAC) supplementation when working to increase their glutathione (GSH) and overall antioxidant levels
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