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Semaglutide: UK regulator approves drug for prevention of cardiovascular events [PMID: 39053933] Laboratory literature summary: Semaglutide: UK regulator approves drug for prevention of cardiovascular events

With regards to specific outcomes such as HF, there has been heterogeneity in the results with both GLP-1RAs and DPP-4i

doi: 10.1371/journal.pone.0058784 169 HansenHHFabriciusKBarkholtPNiehoffMLMorleyJEJelsingJet al

Materials and methods Animals and experimental design Nine-week-old male Fischer 344 rats (Charles River Laboratory, Japan), weighing from 180-200 g, were maintained at 23C, given standard laboratory chow and water ad libitum, and kept under a 12 h light (7:00-19:00)/12 h dark schedule