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They also note that other drugs in the same class as zalfermin, designed slightly differently, may still hold promise and deserve further study

Combined with limited insurance coverage and high out-of-pocket costs, these shortages have prompted some patients to turn to compounded versions as alternatives

Bongini RE, Culver SB, Elkins KM (2007) Engineering aluminum binding affinity in an isolated ef-hand from troponin c: a computational site-directed mutagenesis study