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Mounjaro works similarly to the other drugs in the GLP-1 family, but the medication has a dual-action design, mimicking the action of not one but two incretin hormones involved in blood sugar control: Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

After removing the REWIND trial and the POINEER-6 trial respectively, the pooling effect of dulaglutide and oral semaglutide on the risk of AF would lose statistical significance (Additional file 1: Fig