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9 However, GIP has a distinctly modulatory effect on glucagon by inhibiting its secretion instates of hyperglycaemia, but increasing glucagon release during hypoglycaemia
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Muscle loss is a real risk of rapid weight loss with any mechanism, which is why we counsel patients on protein intake and resistance training during treatment
These medications carry a boxed warning for medullary thyroid carcinoma and are contraindicated in patients with personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2
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