In the decades since, researchers have repeatedly returned to it as an open question in neurochemistry, with one influential review aptly describing it as a "still unresolved riddle" (Kovalzon et al., 2006)
Statements Author contributions EC: Validation, Formal analysis, Writing original draft, Methodology, Supervision, Data curation, Project administration, Writing review & editing, Investigation, Visualization, Software, Conceptualization, Funding acquisition, Resources
LC exerts potent nephroprotective effects against URO-induced renal injury by attenuating oxidative stress, suppressing pro-inflammatory and apoptotic signaling, and promoting anti-apoptotic gene expression
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