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Core design elements may include: A clearly defined mechanistic hypothesis Predefined primary and secondary endpoints Appropriate peptide, copper, and vehicle controls Baseline characterization Randomization and blinding where applicable Validated analytical methods Predefined exclusion criteria Prospective statistical planning Documented deviation procedures Independent replication Interpreting GHK-Cu Research Findings Laboratory observations should not be replaced with cosmetic, regenerative, wound-care, hair, or anti-aging claims that were not directly evaluated
Lancet Neurology
10.1056/NEJM200011163432007 N
NAC, which increases glutathione levels in the brain, improved symptoms of schizophrenia in clinical studies
