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Eur.Rev.Med.Pharmacol Sci 2010;14(4):292-301
GHS-R1a exhibits unusually high constitutive activity it signals to a degree even in the absence of any ligand
In 2009, I reviewed the literature in the field, concluding that at that time no single gene could be clearly linked to the maternal risk of birth of a child with DS, due to the relatively small sample-size and the conflicting nature of the findings among the different studies (Copped, 2009)
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