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Red Flags That Warrant Immediate Discontinuation New-onset psychosis or mania Sustained resting heart rate above 120 bpm Chest pain, syncope, or exertional dyspnea Severe peripheral vasculopathy (Raynaud-like symptoms) Confirmed pregnancy (unless continuation explicitly agreed upon with OB-GYN and psychiatrist) Tapering vs
214 ARF6 negatively regulates ACSL4 expression and regulates gemcitabine resistance by influencing the sensitivity of pancreatic cancer cells to oxidative stress and ferroptosis
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