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Another medication, Orlistat (Xenical and over-the-counter Alli) is a lipase inhibitor not a GLP-1 and differs from the other medications in that it works for obesity management by preventing the absorption of fat in the gastrointestinal tract
Additionally, GLP-1 receptor agonists suppress glucagon secretion from pancreatic alpha cells, further helping to lower blood glucose levels
The development of related inhibitors also plays a role in TMAO regulation Animal experiments showed that inhibition of choline TMA lyase by 3,3-dimethyl-1-butanol (DMB) could reduce plasma TMAO levels and aortic lesions in mice
June 21, 2023
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