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Upon transfection or transduction with genes encoding for one or multiple drug metabolizing enzyme genes, HepG2 cells have been shown to be a valuable model system to study the role of bioactivating enzymes in the cytotoxicity of toxicants (Vignati et al., 2005

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As expected, mGIPR-Ab exposure in the plasma (ICV avg , 14,383 ng g 1 , IP avg , 374,067 ng g 1 ), inguinal white adipose tissue (WAT) (ICV avg , 158.5 ng g 1 , IP avg , 5,496 ng g 1 ) and epididymal WAT (ICV avg , 268.3 ng g 1 , IP avg , 15,423 ng g 1 ) was higher with IP administration (Fig

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