Galvn 3 , Sanjiv Harpavat 4,5 , Moreshwar S Desai 6 and Jorge Antonio Coss-Bu 1 , (1)Baylor College of Medicine, Texas Children's Hospital, Houston, TX, (2)University of Missouri-Columbia, (3)Baylor College of Medicine, Houston, TX, (4)Texas Children's Liver Center - Baylor College of Medicine, Bellaire, TX, (5)Texas Children's Liver Center - Baylor College of Medicine, (6)Baylor College of Medicine Background: Successful early extubation (EE) after liver transplantation (LT) has been shown to reduce ICU and hospital length of stay, infectious and vascular complications, sedation use, and has improved graft and patient survival
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2), further confirming flavan-3,3,4-triol ( 4 ) as the oxidation product of LDOX from 3,4- cis -leucocyanidin ( 6 )
A differentiating feature of this HTC-based approach is the ability, embodied by dHTC1, to prospectively discover noncovalent molecular glues that rely on interfacial proteinprotein contacts that cooperatively stabilize a ternary complex