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Second, translational tool development should focus on dual-functional nanocarriers incorporating motor-neuron-targeting peptides and RVG29, delivering GPX4 activators or mitochondria-targeted iron chelators with ROS/pH-responsive release to achieve lesion-specific delivery and avoid neurotransmitter-synthesis impairment due to non-specific iron depletion
Ledford, D
Acetyl-l-carnitineamelioratesmitochondrial damage and apoptosis following spinal cord injury in rats
Introduction The hypothalamic-pituitary (HP) axis is the central regulator of endocrine action, controlling the function of a number of endocrine glands including thyroid, adrenal, gonadal and the growth hormone (GH)/insulin growth factor-1 (IGF-1) system, which modulate a myriad of physiological processes
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