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Description

Sleep deprivation alters ghrelin and leptin levels (hormones that regulate appetite and digestion), increases cortisol production, and disrupts the circadian rhythm of your gut bacteria

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Exenatide (Byetta, AstraZeneca) is a synthetic version of exendin-4, a GLP-1R agonist found in the saliva of the Gila monster ( Heloderma suspectum )

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Philp D, Kleinman HK

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So Novo Nordisk went back to the drawing board and created semaglutide

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