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While gastrointestinal symptoms dominate the adverse effect profile, patients and clinicians have increasingly questioned whether these medications might contribute to musculoskeletal complaints, including muscle pain, weakness, or discomfort

However, for those undergoing IV therapy for specific health concerns, such as chronic fatigue or nutrient deficiencies, the effects might necessitate regular sessions to maintain

Nevertheless, these evaluations often depend on short-term trial results projected across lifetime horizons, so injecting uncertainty over long-term efficacy and safety