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Nausea, diarrhea, constipation, and fatigue are the most reported issues
The SURPASS clinical trial program demonstrated that tirzepatide at its highest dose (15 mg weekly) produced average weight loss of 20-25% of body weight, significantly exceeding the results seen with GLP-1 only agonists
Acute stress and large meals trigger GLP-1 in the brain to suppress appetite, preventing overeating
GLP-1 is a hormone the body already produces naturally in response to food
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