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References Lall, S., Tung, L

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One of the central regulators in this process is hypoxia-inducible factor-1 alpha (HIF-1), a transcription factor that senses low oxygen levels and triggers the expression of genes involved in angiogenesis, metabolism, and cell survival

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Impacts among markets differ due to factors including differences in the current obesity rates and future expected obesity trends, medication uptake (cost and eligibility), and the cause-of-death mix

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