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PMC+2PMC+2 The authors conclude that while laboratory results are intriguing, human safety is unknown, and unregulated compounding introduces risks of contamination, mislabeling and dose inconsistency

Recommendations for future research Future research studies should prioritise adequately powered, multicentre, double-blind RCTs of NAC in PD with rigorous controls, standardised dosing regimens, clearly defined routes of administration, and stratification by disease stage and baseline oxidative stress markers to identify patient subgroups most likely to benefit

Berkowitz, S., et al

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