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Name: tirzepatide alzheimers attenuates neurotoxicity by suppressing inflammation, apoptosis and restoring neurotrophin expression in an Alzheimer's disease-like rat model | Metabolic Brain Disease tirzepatide dementia study Tirzepatide: a
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Asterholm IW, Mundy DI, Weng J, Anderson RG, Scherer PE (2012) Altered mitochondrial function and metabolic inflexibility associated with loss of caveolin-1

Infiltrating cells in the CNS interact with pathologically deposited -synuclein molecules, which activate pattern-recognition receptors (TLR2, TLR4) on monocytes and microglia, increasing NF-B activation and inflammasome signaling (NLRP3) [127]