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As our understanding of this relationship grows, it will enhance the ability of healthcare providers to optimize diabetes treatment while minimizing adverse effects on sleep, ultimately improving the quality of life for patients with type 2 diabetes
This regulatory circuit concurrently increases the expression of the immune checkpoint molecule poliovirus receptor (PVR, CD155), thereby further promoting immune evasion in addition to metabolic reprogramming [80]
doi:10.1038/nm727 26
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