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doi: 10.1093/ehjcvp/pvac018 302 ShenoyS
These advanced agents are designed to target multiple incretin receptors to achieve superior efficacy
In fact, in the context of IBD, inducing such an M2 macrophage skew via PDEVs correlates with enhanced resolution of colitis: for instance, GsDEVs treatment in mice with colitis increased IL-10 release from intestinal macrophages, which in turn helped quell intestinal inflammation [133]
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