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Importantly, nuclear-localized FOXO4-positive Leydig cells in elderly testes showed reduced expression of 3-HSD, a rate-limiting enzyme in testosterone synthesis, implying a connection between nuclear FOXO4 and age-related decline in testosterone production [1]

Hepatic encephalopathy, as a consequence of advanced liver disease, is the major manifestation of the perturbed brain-gut microbiome axis

This superior contraction in the TCC group was maintained and significantly higher than in the control group on days 7, 14, and 21

The hepatocyte growth factor (HGF)/c-Met receptor system as a therapeutic target in the treatment of neurodegenerative diseases