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And critically for obesity research, it acts centrally: amylin binds to receptors in the area postrema and the brainstem, where it generates satiety signals that communicate to the brain that the body has had enough to eat
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J Cell Sci
Despite its importance, B12 deficiency is remarkably common particularly among vegetarians, older adults, individuals with digestive conditions, and anyone whose body has difficulty absorbing this vitamin from food or oral supplements
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