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If you see blood in the syringe remove the needle and syringe and apply moderate pressure for about a minute
For those with irreversible causes such as pernicious anaemia or malabsorption, injections are usually given every 23 months
The speed of response depends on factors including the severity and duration of deficiency, the presence of neurological complications, and individual metabolic differences
[2] Age and overall health status also play important roles
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