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185 To circumvent resistance and expand the scope of DDR targeting, next-generation agents such as ATR, CHK1, WEE1, and DNA-PK inhibitors are being investigated, both as monotherapies and in combination with DNA-damaging agents
Its level decreases with age (especially from the age of 45-50) and as the body's defence needs increase (immunity, liver detoxification, antioxidant defences...)
Noguchi T, Katoh H, Nomura S, Okada K, Watanabe M (2024) The GLP-1 receptor agonist exenatide improves recovery from spinal cord injury by inducing macrophage polarization toward the M2 phenotype
Semaglutide GLP-1 works by mimicking the natural hormone GLP-1, which helps reduce appetite, increase feelings of fullness, and slow digestion, leading to reduced calorie intake and healthier eating habits
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