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Although ApoE4 has been shown to disrupt Blood Brain Barrier (BBB) integrity and reduce its glucose uptake (Brandon et al., 2018), relatively few studies have investigated the effect of ApoE on cerebrovascular FAO bioenergetics

Time-to-event analyses HRs for event-based outcomes comparing semaglutide 2.4 mg versus placebo were estimated from a pre-specified Cox proportional hazards model with treatment group (semaglutide and placebo) as a binary variable, presented with two-sided 95% CIs and two-sided P values

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