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This provides a potential pathway for the entry of gut microbiota and its metabolites into the brain
The study enrolled 147 patients aged 1875 years with diagnosed UC at least 90 days prior to randomization, total MS 6 including MES 2, who were non-hospitalized and treated with stable background UC therapy containing 5-aminosalicylates and/or low-dose glucocorticosteroids and/or purine analogues, with exclusions for pregnant/breastfeeding women, history of colostomy, current diagnosis of indeterminate colitis or CD, hepatitis B/C or HIV, and history of cancer
In 2014, Beck et al
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