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**Supplements are not substitutes to a healthy, nutritious and balanced diet
This pattern aligns with findings from CANVAS [42], CREDENCE [60], and DAPA-CKD [58], in which greater absolute eGFR preservation was noted in participants with higher baseline albuminuria
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Detailed interaction analysis revealed that amiodarone stabilizes within the active pockets of each protein through multiple non-covalent interactions, including hydrogen bonds, extensive hydrophobic contacts, - stacking, and van der Waals forces, providing preliminary insight into its potential multi-target mechanism
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