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Copper overload: Theoretically possible with high-dose systemic use, though not documented at typical topical concentrations
Xie et al., 2023)
The composition of your body matters, too
FasL binding induces the trimerization of Fas, which recruits the adaptor protein FADD (Fas-associated death domain) and the initiator caspase-8 or caspase-10, which are oligomerized and activated through autocatalysis
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