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If pricing transparency is a dealbreaker, clinics like MEDVi list every price up front
What the human data does and does not show Human evidence falls into three buckets: the randomized trials that got these drugs approved, large observational database studies, and ongoing pharmacovigilance
Surgery (colectomy ) is only considered for non-anatomical causes of constipation, when all other conservative options are exhausted and the constipation is severe
You can continue if the overall trend shows improvement even if not yet resolved
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