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Semaglutide doesn't reduce stomach acid, but if you're also taking a PPI for reflux (common on GLP-1 medications), absorption may decrease
This has led to the exploration of a potential connection between incretin hormones and bone tissue, referred to as the entero-endocrine-osseous axis
However, patients with thyroid nodules noted on physical examination or imaging should be referred to an endocrinologist for further evaluation
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