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This CNS-mediated pro-sexual mechanism is mechanistically upstream of, and independent from, the nitric oxide/cGMP/PDE5 pathway targeted by sildenafil (Viagra), tadalafil (Cialis), and other PDE5 inhibitors which act at the vascular/penile smooth muscle level as downstream effectors of a pre-existing arousal signal
Cardiovascular Safety : The cardiovascular safety of tirzepatide has been evaluated and confirmed to date through a pre-specified meta-analysis of phase 2 and 3 randomized trials comparing tirzepatide with other placebo, insulin glargine, degludec, semaglutide, dulaglutide for a minimum of 26 weeks (including the GPGB, SURPASS 1,2,3,4,5, and J-mono studies) [67]
Afterward, well hold pressure and apply a bandage per your preference
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