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This 92-person trial is the closest thing to a head-to-head decomposition of the combination that exists, and its most interesting result is the negative one: on the primary glycaemic endpoint, adding cagrilintide to semaglutide did not produce a statistically significant improvement over semaglutide alone
It was first FDA-approved in 2010 under the brand name Egrifta for HIV-associated lipodystrophy, a condition causing excess visceral fat accumulation
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Mainly, women often experience excellent results due to hormonal factors
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