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[9] Tsuiji, K

In individuals with obesity, GLP-1 secretion from intestinal L-cells may itself be impaired meaning the body is already deficient in the very hormone these medications replace

Preventing under-eye circles involves practicing good skincare habits such as using sunscreen and gentle moisturizers, getting enough sleep, managing allergies, staying hydrated, avoiding smoking and excessive alcohol, and addressing any underlying health issues contributing to the dark circles

On the other hand, iron is a prooxidant and can increase OS in the brain by participating in Fentons reaction and contributing to the formation of reactive oxygen species (ROS)