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Ergot poisoning has been known for centuries
This revealed that a peripheral loop in the N-terminal domain of CRBN (amino acids 146153) is brought closer to the ENL YEATS domain than in any other structure (median root-mean-square deviation (r.m.s.d.) = 3.8 ) and contributes to the high degree of shape complementarity between CRBN and ENL (Fig
Jarosiewicz et al
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